Early sedation with dexmedetomidine in patients with acute myocardial infarction requiring mechanical ventilation.

Abstract

Patients with acute myocardial infarction (AMI) who require invasive mechanical ventilation (IMV) represent a critically ill population with limited data on optimal sedative and analgesic use. Clinical trials assessing dexmedetomidine use exclude poorly represent patients with AMI. This study aimed to compare the use of early sedation with dexmedetomidine with usual care sedation in patients with AMI requiring IMV. We utilized the Vizient® Clinical Data Base to identify patients aged ≥18 years a