Toward a unified gait freeze index: a standardized benchmark for clinical and regulatory evaluations.

Abstract

Freezing of Gait (FOG) is a disabling motor symptom that affects a majority of individuals with advanced Parkinson's disease, severely limiting mobility, independence, and quality of life. Automatic methods for detecting FOG using the freeze index (FI) have been widely proposed to systematically monitor FOG in real life and guide therapy optimizations. However, methods to estimate the FI have relied on a broad range of measurement technologies and computational methodologies, often lacking mathe