Folate mediates cognitive impairment of aged people with periodontitis.

Abstract

Periodontitis is associated with poorer cognitive function. It remains unclear whether folate plays a crucial role in periodontitis-promoted cognitive impairment (CI) in the elderly population. Data for this cross-sectional population-based study were obtained from the National Health and Nutrition Examination Survey (NHANES), 2011-2014 database. Associations between periodontitis and cognitive scores, exogenous folate (dietary intake folate equivalents and dietary supplement folate), and endoge