Use of the Learning Health System to Redesign and Implement a Clinical Decision Support System for Antimicrobial Stewardship.

Abstract

Antimicrobial resistance is a significant global health issue, and Antimicrobial Stewardship (AMS) services in hospitals are key to addressing this. Clinical Decision Support Systems (CDSS) are vital tools that support AMS programs. Guidance MS, a CDSS developed in 2005, has been implemented in over 60 Australian hospitals, yielding positive outcomes such as reduced gram-negative resistance, decreased antimicrobial consumption, and improved prescribing practices. This CDSS was redesigned to cont