Opportunities and Challenges in Precision Neurotherapeutics.

Abstract

Precision neurotherapeutics represents a transformative paradigm shift from standardized "one-size-fits-all" treatments of neurological, neurodegenerative, and/or psychiatric disorders toward individualized interventions that leverage patient-specific biological, behavioral, and physiological characteristics. Traditional neurotherapeutic approaches achieve modest response rates of 30-60% for first-line treatments, necessitating personalized strategies that account for individual differences in g