Improving the transparency of animal experiments: valuable lessons learned from a systematic analysis of registration protocols.

Abstract

To comprehensively analyze the epidemiological characteristics of research protocols on international animal experiment registration platforms, explore potential factors influencing protocol publication, and offer recommendations to improve animal experiment registration systems. Research protocols registered on the Netherlands’ PCT(Preclinical Trials) and Germany’s ASR(Animal Study Registry) animal experiment registration platforms up to December 30, 2024, were included. Relevant data were extr