Interpreting the two-hour partial REBOA safety window: Physiologic context, monitoring limitations, and device-specific considerations.

Abstract

Recent updates to the Joint Trauma System clinical practice guidelines for resuscitative endovascular balloon occlusion of the aorta incorporate partial aortic occlusion (PAO) for up to two hours in combat casualty care following US Food and Drug Administration 510(k) clearance of the pREBOA-PRO catheter for partial Zone 1 occlusion under defined physiologic parameters. The FDA clearance specifies physiologic targets, including proximal systolic blood pressure of 90 to 110 mm Hg and distal systo