Image-based evaluation of a commercial AI synthetic CT generator for brain and prostate MR-only radiotherapy.
PMID: 42547906 ·
Morgan Aire, Carson Matthews, Joshua Jones, David Duong, Christopher Schneider, Sotirios Stathakis, Olivia Shay, Krystal Kirby
Abstract
Synthetic CTs (sCT) were developed to provide electron density information for MR-only treatment planning. Some AI-based sCT generators have received FDA-clearance and better capture tissue heterogeneity through voxel-wise mappings to improve image guidance and dose calculation. To quantitatively characterize the image quality and geometric surrogate agreement of an FDA 510(k) cleared AI-based synthetic CT generator (TheraPanacea) for brain and prostate MR-only radiotherapy, using per-structure
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