PubMed

Strategies for antimicrobial peptide coatings on medical devices: a review and regulatory science perspective.

PMID: 33070659 · 2020-10-18

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ЖурналCritical reviews in biotechnology

Год2020-10-18

PMID33070659

Аннотация

Indwelling and implanted medical devices are subject to contamination by microbial pathogens during surgery, insertion or injection, and ongoing use, often resulting in severe nosocomial infections. Antimicrobial peptides (AMPs) offer a promising alternative to conventional antibiotics to reduce the incidence of such infections, as they exhibit broad-spectrum antimicrobial activity against Gram-negative and Gram-positive bacteria, microbial biofilms, fungi, and viruses. In this review-perspectiv

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