Feasibility of Superior Rectal Artery Embolization for the Treatment of Hemorrhoidal Disease
NCT: NCT02303925 · COMPLETED
Brief Summary
With an estimated prevalence between 4 and 35%, the hemorrhoidal disease is the most frequent proctologic disease. Its symptoms are mainly rectorrhagia, externalization of the hemorrhoidal cushions (muco-hemorrhoidal prolapse), and/or pain and pruritus. Its acute complications (external and/or internal thromboses) are unpredictable. Surgical treatment concerns approximately 10% of patients with diagnosed hemorrhoidal pathologies. The elective ligature of the arteria haemorrhoidalis under trans-anal Doppler scanning was developed in order to reduce the postoperative morbidity of hemorrhoidal surgery. This technique consists in a ligation of the superior rectal artery under Doppler control in order to decrease the blood flow within the hemorrhoids and therefore to reduce them. It is effective in the treatment of internal hemorrhoidal pathology without prolapse (grade II). The complications rate is low and estimated between 2 and 12% : rectorrhagia (4.3%), thrombosed hemorrhoids (1,8%), fissure (0,8%), acute urine retention (0,7%). With the major advances in interventional radiology such ligation could be performed by an endovascular coil embolization. Until now no direct study exists on the subject but several case reports show the feasibility of an embolization of the superior rectal arteries for rectorrhagia of various etiologies such as the hemorrhoidal disease. Endovascular access should increase the selectivity of the embolization compared to the Doppler scanning technique. Indeed the arteriography makes it possible to scan all branches of the superior rectal artery and therefore to occlude permanently the branches that feed the hemorrhoidal plexuses. Moreover the endovascular embolization technique should avoid the main complications of the trans-anal access technique. The primary objective of this study is : the assessment of the efficacy of endovascular coil embolization of the superior rectal arteries in the management of the symptoms of the hemorrhoidal disease grade II and III. The secondary objective is : the assessment of postoperative complications.
Frequently Asked Questions
What is Feasibility of Superior Rectal Artery Embolization for the Treatment of Hemorrhoidal Disease?
Feasibility of Superior Rectal Artery Embolization for the Treatment of Hemorrhoidal Disease is a clinical trial registered under NCT02303925. Current status: COMPLETED.
What is the status of NCT02303925?
The current status of NCT02303925 (Feasibility of Superior Rectal Artery Embolization for the Treatment of Hemorrhoidal Disease) is: COMPLETED.
When did Feasibility of Superior Rectal Artery Embolization for the Treatment of Hemorrhoidal Disease start?
Feasibility of Superior Rectal Artery Embolization for the Treatment of Hemorrhoidal Disease started on 2014-12-14.
Official Source
View on ClinicalTrials.gov →Data sourced from ClinicalTrials.gov API. For the most current status, refer to the official record.