Neural Mechanisms of Intermittent Theta Burst Stimulation in the Core Depression Network
NCT: NCT05224206 · ACTIVE_NOT_RECRUITING
Brief Summary
Repetitive Transcranial magnetic stimulation (TMS) uses magnetic fields to modulate brain activity. A novel form of repetitive TMS (rTMS), intermittent theta burst stimulation (iTBS), has emerged as a promising new treatment for depression. This technique may be advantageous due to its very short duration and potentially stronger effect on brain activity in comparison with standard rTMS. However, the exact effect of iTBS on the activity of the brain in clinical populations remains poorly understood. This project aims to improve understanding of the mechanisms of action of iTBS by comparing its neuronal effect to sham treatment in 22 individuals with a diagnosis of major depressive episode, using positron emission tomography (PET) and magnetic resonance imaging (MRI) in a double-blind cross-over experiment, followed by a 6-week daily treatment course of iTBS.
Frequently Asked Questions
What is Neural Mechanisms of Intermittent Theta Burst Stimulation in the Core Depression Network?
Neural Mechanisms of Intermittent Theta Burst Stimulation in the Core Depression Network is a clinical trial registered under NCT05224206. Current status: ACTIVE_NOT_RECRUITING.
What is the status of NCT05224206?
The current status of NCT05224206 (Neural Mechanisms of Intermittent Theta Burst Stimulation in the Core Depression Network) is: ACTIVE_NOT_RECRUITING.
When did Neural Mechanisms of Intermittent Theta Burst Stimulation in the Core Depression Network start?
Neural Mechanisms of Intermittent Theta Burst Stimulation in the Core Depression Network started on 2023-04-26.
Official Source
View on ClinicalTrials.gov →Data sourced from ClinicalTrials.gov API. For the most current status, refer to the official record.