Effect of Early Saline Lavage on Synovial Fluid Composition Following Intra Articular Ankle Fractures
NCT: NCT05465382 · TERMINATED
Brief Summary
The purpose of this study is to examine the effect of early, percutaneous, intra-articular saline lavage on the undiluted synovial fluid microenvironment during the acute phase following intra-articular fracture of the human ankle. We hypothesize that early intervention with percutaneous joint lavage in the first 0-48 hours after injury will attenuate the production of pro-inflammatory cytokines, MMP's and cartilage breakdown products compared to non-lavaged control subjects at the time of surgical fixation.
Frequently Asked Questions
What is Effect of Early Saline Lavage on Synovial Fluid Composition Following Intra Articular Ankle Fractures?
Effect of Early Saline Lavage on Synovial Fluid Composition Following Intra Articular Ankle Fractures is a clinical trial registered under NCT05465382. Current status: TERMINATED.
What is the status of NCT05465382?
The current status of NCT05465382 (Effect of Early Saline Lavage on Synovial Fluid Composition Following Intra Articular Ankle Fractures) is: TERMINATED.
When did Effect of Early Saline Lavage on Synovial Fluid Composition Following Intra Articular Ankle Fractures start?
Effect of Early Saline Lavage on Synovial Fluid Composition Following Intra Articular Ankle Fractures started on 2022-07-22.
Official Source
View on ClinicalTrials.gov →Data sourced from ClinicalTrials.gov API. For the most current status, refer to the official record.