Deep rTMS Modulating Insula Synaptic Density and Smoking Behavior in Schizophrenia
NCT: NCT05724810 · TERMINATED
Brief Summary
Purpose of the study: Evaluate the effect of deep repetitive transcranial magnetic stimulation (deep rTMS; hereafter abbreviated as "dTMS") on synaptic density measured with positron emission tomography (PET) and the radiotracer \[11C\]UCB-J. The investigators also seek to link plasticity changes in the regions targeted by the electric field (especially, the insula) to changes in the functioning of insula circuits and behavioral cigarette usage in patients with schizophrenia (SCZ). Importance of the study: This is the first study designed to directly evaluate the mechanism of action (MOA) of dTMS for smoking disruption in patients with SCZ. Patients with SCZ are a vulnerable population in high, immediate need of new smoking therapeutics for reducing premature morbidity and mortality.
Frequently Asked Questions
What is Deep rTMS Modulating Insula Synaptic Density and Smoking Behavior in Schizophrenia?
Deep rTMS Modulating Insula Synaptic Density and Smoking Behavior in Schizophrenia is a clinical trial registered under NCT05724810. Current status: TERMINATED.
What is the status of NCT05724810?
The current status of NCT05724810 (Deep rTMS Modulating Insula Synaptic Density and Smoking Behavior in Schizophrenia) is: TERMINATED.
When did Deep rTMS Modulating Insula Synaptic Density and Smoking Behavior in Schizophrenia start?
Deep rTMS Modulating Insula Synaptic Density and Smoking Behavior in Schizophrenia started on 2023-04-04.
Official Source
View on ClinicalTrials.gov →Data sourced from ClinicalTrials.gov API. For the most current status, refer to the official record.