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Clinical Trial

Motor and Neurophysiological Changes After Ischemic Conditioning in Individuals With Stroke

NCT: NCT05906602 · COMPLETED

NCT IDNCT05906602
StatusCOMPLETED
Start Date2024-05-20
Completion2025-12-31

Brief Summary

The goal of this clinical trial is to test ischemic conditioning (blood flow restriction) as a neuromodulatory technique to improve gait function in stroke. Neuromodulation is emerging as a promising adjunct strategy to facilitate changes in brain activity and improve motor behavior following a neurological injury such as stroke. The main questions this trial aims to answer are: * Can ischemic conditioning produce neuromodulatory changes in the lower limb primary motor cortex? * Can ischemic conditioning be used as a neuromodulatory technique to improve strength and motor control in individuals with stroke when compared to sham ischemic conditioning? Participants will take part in two sessions of ischemic conditioning where a cuff (similar to ones that measure blood pressure) will be placed around the thigh and inflated to one of two blood flow restriction pressures (real ischemic conditioning (real IC) and sham ischemic conditioning (sham IC)). Each participant will experience measures of brain activity and motor behavior testing before and after both sessions (real IC and sham IC). Researchers will investigate ischemic conditioning as neuromodulation modality in stroke to see if ischemic conditioning can produce beneficial changes in brain activity and improvements on subsequent motor behavior tasks.

Frequently Asked Questions

What is Motor and Neurophysiological Changes After Ischemic Conditioning in Individuals With Stroke?

Motor and Neurophysiological Changes After Ischemic Conditioning in Individuals With Stroke is a clinical trial registered under NCT05906602. Current status: COMPLETED.

What is the status of NCT05906602?

The current status of NCT05906602 (Motor and Neurophysiological Changes After Ischemic Conditioning in Individuals With Stroke) is: COMPLETED.

When did Motor and Neurophysiological Changes After Ischemic Conditioning in Individuals With Stroke start?

Motor and Neurophysiological Changes After Ischemic Conditioning in Individuals With Stroke started on 2024-05-20.

Official Source

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Data sourced from ClinicalTrials.gov API. For the most current status, refer to the official record.