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Clinical Trial

rTMS and Cognitive-behavioral Therapy for Cocaine Use Disorder

NCT: NCT05974202 · NOT_YET_RECRUITING

NCT IDNCT05974202
StatusNOT_YET_RECRUITING
Start Date2026-05-01
Completion2028-04-28

Brief Summary

The goal of this clinical trial is to compare the effects of active repetitive transcranial magnetic stimulation (rTMS) to sham (placebo) rTMS prior to cognitive-behavioral therapy (CBT) as a treatment for adults with cocaine use disorder. The main questions it aims to answer are: * Is rTMS safe and feasible as an augmentation for CBT for the treatment of cocaine use disorder? * What is the brain mechanism of rTMS? * Will active rTMS (compared to sham rTMS) followed by CBT help adults with cocaine use disorder achieve abstinence from cocaine? Participants will: * Have two brain MRI scans; * Undergo 3 weeks of daily rTMS (or sham) treatments (15 sessions), and; * Have 12 weeks of once-weekly cognitive-behavioral therapy for the treatment of cocaine use disorder. Researchers will compare active (real) rTMS to sham (placebo) rTMS. All participants will receive cognitive-behavioral therapy. The former principle investigator, Dr. Derek Blevins, has vacated his position (February 2025), and has transferred the principle investigator role to Dr. John Mariani, the STARS Clinic Director.

Frequently Asked Questions

What is rTMS and Cognitive-behavioral Therapy for Cocaine Use Disorder?

rTMS and Cognitive-behavioral Therapy for Cocaine Use Disorder is a clinical trial registered under NCT05974202. Current status: NOT_YET_RECRUITING.

What is the status of NCT05974202?

The current status of NCT05974202 (rTMS and Cognitive-behavioral Therapy for Cocaine Use Disorder) is: NOT_YET_RECRUITING.

When did rTMS and Cognitive-behavioral Therapy for Cocaine Use Disorder start?

rTMS and Cognitive-behavioral Therapy for Cocaine Use Disorder started on 2026-05-01.

Official Source

View on ClinicalTrials.gov →

Data sourced from ClinicalTrials.gov API. For the most current status, refer to the official record.