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Clinical Trial

Home-based tDCS in Frontotemporal Dementia or Alzheimer's Disease

NCT: NCT05978804 · TERMINATED

NCT IDNCT05978804
StatusTERMINATED
Start Date2023-08-10
Completion2025-09-10
SponsorJohns Hopkins University (OTHER)
First posted
Last updated

Brief Summary

The primary objective of this research is to evaluate the effects of non-invasive brain stimulation and computerized cognitive training on executive functioning in individuals with Primary Progressive Aphasia (PPA), mild cognitive impairment (MCI), or dementia. In this study, investigators will use transcranial direct current stimulation (tDCS) to stimulate the left dorsolateral prefrontal cortex (DLPFC). Previous studies have demonstrated that tDCS over the DLPFC led to improvements in attention deficit caused by stroke, Parkinson's Disease, and major depression as well as language deficits caused by neurodegenerative conditions such as primary progressive aphasia or mild cognitive impairment. The investigators seek to expand on this literature by investigating how anodal tDCS paired with and without cognitive training will impact executive functioning in PPA with Frontotemporal Dementia or Alzheimer's Disease pathology and Mild Cognitive Impairment/Alzheimer's Disease (e.g. shifting, updating, monitoring, and manipulation).

Official Source

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Data sourced from ClinicalTrials.gov API. For the most current status, refer to the official record.

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