ORIF Distal Radius Blood Flow Restriction Therapy
NCT: NCT06136286 · ACTIVE_NOT_RECRUITING
Brief Summary
Patients commonly experience a significant amount of muscular atrophy following open reduction internal fixation (ORIF) surgery of distal radius fractures, associated with an increased risk of re-injury, and an increase in time of recovery. A combination of low intensity resistance exercise and blood flow restriction (BFR) therapy has been shown to elicit responses similar to high intensity resistance exercise with reduced risk. We hypothesize that chronic low intensity resistance exercise combined with BFR will improve muscular strength, reduce skeletal muscle atrophy, and will enhance recovery. Therefore, the specific aims of this study are as follows: 1. Determine if BFR added to standard post-operative rehab will prevent skeletal muscle atrophy and promote skeletal muscle growth during 12-weeks of rehab training compared to traditional rehab alone. The working hypothesis, founded on previous literature, is that combined rehab and BFR will enhance skeletal muscle growth and prevent atrophy to a greater extent than rehab alone. 2. Determine if BFR added to standard post-operative rehab will improve muscular strength following surgery compared to traditional rehab alone. Because strength can be attributed to skeletal muscle mass, the working hypothesis, founded on previous literature, is that combined rehab and BFR will enhance skeletal muscle strength and fatigue resistance to a greater extent than rehab alone. 3. Determine if BFR added to standard post-operative rehab will improve functional outcomes following surgery compared to traditional rehab alone. The working hypothesis, founded on previous literature is that BFR will improve functional outcomes over rehab alone.
Frequently Asked Questions
What is ORIF Distal Radius Blood Flow Restriction Therapy?
ORIF Distal Radius Blood Flow Restriction Therapy is a clinical trial registered under NCT06136286. Current status: ACTIVE_NOT_RECRUITING.
What is the status of NCT06136286?
The current status of NCT06136286 (ORIF Distal Radius Blood Flow Restriction Therapy) is: ACTIVE_NOT_RECRUITING.
When did ORIF Distal Radius Blood Flow Restriction Therapy start?
ORIF Distal Radius Blood Flow Restriction Therapy started on 2019-10-22.
Official Source
View on ClinicalTrials.gov →Data sourced from ClinicalTrials.gov API. For the most current status, refer to the official record.