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Clinical Trial

Mechanically or Kinematically Aligned Total Knee Prosthesis

NCT: NCT06158646 · RECRUITING

NCT IDNCT06158646
StatusRECRUITING
Start Date2023-10-05
Completion2027-09-30

Brief Summary

The mechanical alignment technique (Mechanical Alignment - MA) of a total knee prosthesis (TKA) was developed with the aim of making the installation of a TKA simple and reproducible, and that the prosthetic biomechanics are acceptable, thus promoting good longevity of implants. This is a technique that does not aim to restore the constitutional anatomy of the knee; bone cuts are systematically made at fixed angles, in the 3 planes of space, in relation to the mechanical axes of the long bones (femur and tibia). This non-personalized implantation technique therefore systematically alters the anatomy, laxity and kinematics of the knee, causing up to 50% of residual symptoms after prosthetic implantation and 20% of dissatisfied patients. In order to improve the clinical results of TKA, a new, more personalized and physiological technique was developed in 2007, called Kinematic Alignment (KA). This technique aims to restore the pre-arthritic anatomy, unique to each knee. Patients with severe constitutional deformity of the lower limb therefore retain this deformity after kinematic prosthetic replacement. The impact of the alignment technique on the biomechanics of the prosthetic knee remains poorly described. The main objective of this study is therefore to compare knee biomechanics between mechanical TKA and kinematic TKA.

Frequently Asked Questions

What is Mechanically or Kinematically Aligned Total Knee Prosthesis?

Mechanically or Kinematically Aligned Total Knee Prosthesis is a clinical trial registered under NCT06158646. Current status: RECRUITING.

What is the status of NCT06158646?

The current status of NCT06158646 (Mechanically or Kinematically Aligned Total Knee Prosthesis) is: RECRUITING.

When did Mechanically or Kinematically Aligned Total Knee Prosthesis start?

Mechanically or Kinematically Aligned Total Knee Prosthesis started on 2023-10-05.

Official Source

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Data sourced from ClinicalTrials.gov API. For the most current status, refer to the official record.