Fatigue Alleviation Through Neuromodulating Therapy in Multiple Sclerosis
NCT: NCT06569550 · RECRUITING
Brief Summary
The goal of this clinical trial is to learn if repetitive Transcranial Magnetic Stimulation (rTMS) of the left premotor cortex can lessen fatigue in patients with Multiple Sclerosis, and if this is a feasible intervention. It will also give further information on fatigue in Multiple Sclerosis. The main questions it aims to answer is: * Does premotor rTMS decrease fatigue symptoms in patients with Multiple Sclerosis? * Is the change in fatigue reflected in an altered balance between brain excitation and inhibition in the targeted premotor cortex? Researchers will compare real rTMS with sham rTMS (which does not stimulate with a magnetic field), to see if real rTMS works to alleviate fatigue. Participants will: * Receive real or sham rTMS for 30 minutes, 5 days in a row * Visit the clinic before and 6 days after for baseline and follow-up * Fill out on-line questionnaires 1 day and 4 weeks after the end of intervention * Undergo a total of 3 brain scans (Magnetic Resonance Imaging at ultra-high field), at baseline, end of intervention, and follow-up * Undergo lab neurophysiological measurements before and after the first intervention session * Keep a fatigue diary and wear an activity tracker in the period before and after the intervention
Frequently Asked Questions
What is Fatigue Alleviation Through Neuromodulating Therapy in Multiple Sclerosis?
Fatigue Alleviation Through Neuromodulating Therapy in Multiple Sclerosis is a clinical trial registered under NCT06569550. Current status: RECRUITING.
What is the status of NCT06569550?
The current status of NCT06569550 (Fatigue Alleviation Through Neuromodulating Therapy in Multiple Sclerosis) is: RECRUITING.
When did Fatigue Alleviation Through Neuromodulating Therapy in Multiple Sclerosis start?
Fatigue Alleviation Through Neuromodulating Therapy in Multiple Sclerosis started on 2024-08-14.
Official Source
View on ClinicalTrials.gov →Data sourced from ClinicalTrials.gov API. For the most current status, refer to the official record.