Paired Vagus Nerve Stimulation Mechanisms
NCT: NCT06716112 · TERMINATED
Brief Summary
In this mechanistic study, 40 individuals with chronic stroke will be implanted with a small vagus nerve stimulation (VNS) device. The study will use a randomized, blinded, crossover design to deliver two conditions in six-week blocks: active VNS or sham VNS, each paired with upper extremity (UE) motor rehabilitation. Assessment visits will occur before and after each block, and will examine neural pathway strength, functional connectivity, and motor and non-motor behaviors. Investigators will test for VNS-induced changes in motor, cognitive, and affective systems, and will identify biomarkers predictive of clinical response.
Frequently Asked Questions
What is Paired Vagus Nerve Stimulation Mechanisms?
Paired Vagus Nerve Stimulation Mechanisms is a clinical trial registered under NCT06716112. Current status: TERMINATED.
What is the status of NCT06716112?
The current status of NCT06716112 (Paired Vagus Nerve Stimulation Mechanisms) is: TERMINATED.
When did Paired Vagus Nerve Stimulation Mechanisms start?
Paired Vagus Nerve Stimulation Mechanisms started on 2025-07-15.
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Official Source
View on ClinicalTrials.gov →Data sourced from ClinicalTrials.gov API. For the most current status, refer to the official record.