Disclaimer: This site aggregates publicly available data from official government sources (FDA, ClinicalTrials.gov, PubMed, SEC EDGAR, NMPA) for general reference only. It does NOT constitute medical advice, diagnosis, treatment recommendations, or investment advice.

Clinical Trial

Novel Brain Stimulation Treatment for Neuropsychiatric Symptoms in Alzheimer's Disease

NCT: NCT06835283 · RECRUITING

NCT IDNCT06835283
StatusRECRUITING
Start Date2026-08-01
Completion2027-08

Brief Summary

The goal of this pilot study is to test a combination of two non-invasive brain stimulation methods, called iTBS (intermittent theta burst stimulation) and tDCS (transcranial direct current stimulation), in people with Alzheimer's Disease (AD) and related dementias (ADRD). This study will also explore whether the combined treatment shows promise for reducing neuropsychiatric symptoms like mood swings, apathy, and agitation, and will evaluate the impact of the treatment on caregivers. The main questions the study aims to answer are: 1. Is the combined brain stimulation treatment practical and well-tolerated? 2. Do preliminary results suggest that this treatment could help manage neuropsychiatric symptoms and support a larger study? Participants will: * Attend nine in-person visits over three months. * Complete one week of in-clinic brain stimulation sessions (iTBS) followed by four weeks of daily at-home brain stimulation sessions (tDCS). * Take part in brain scans, questionnaires, and brain activity tests before and after the treatment. This pilot study is a first step to assess whether this combined treatment approach is practical and whether it has potential to improve symptoms, laying the groundwork for larger studies in the future.

Frequently Asked Questions

What is Novel Brain Stimulation Treatment for Neuropsychiatric Symptoms in Alzheimer's Disease?

Novel Brain Stimulation Treatment for Neuropsychiatric Symptoms in Alzheimer's Disease is a clinical trial registered under NCT06835283. Current status: RECRUITING.

What is the status of NCT06835283?

The current status of NCT06835283 (Novel Brain Stimulation Treatment for Neuropsychiatric Symptoms in Alzheimer's Disease) is: RECRUITING.

When did Novel Brain Stimulation Treatment for Neuropsychiatric Symptoms in Alzheimer's Disease start?

Novel Brain Stimulation Treatment for Neuropsychiatric Symptoms in Alzheimer's Disease started on 2026-08-01.

Official Source

View on ClinicalTrials.gov →

Data sourced from ClinicalTrials.gov API. For the most current status, refer to the official record.