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Clinical Trial

Paired Comparison of SVV and PVI Accuracy

NCT: NCT07260890 · COMPLETED

NCT IDNCT07260890
StatusCOMPLETED
Start Date2025-10-01
Completion2026-05-20

Brief Summary

This study will compare two operating-room monitors-stroke volume variation (SVV, from the arterial line) and the Pleth Variability Index (PVI, from the pulse oximeter)-to see which one more accurately predicts whether giving a small fluid bolus will improve the heart's pumping during laparoscopic major abdominal surgery. Adults having elective surgery under general anesthesia will receive two small, timed 250-mL crystalloid infusions as part of routine care (one before and one after creation of the pneumoperitoneum). The research team will record SVV and PVI values just before and three minutes after each infusion while keeping these readings hidden from the clinicians so that usual care is not changed. No experimental drugs or devices are used. The main goal is to learn which index better identifies "fluid responsiveness," so future care can be safer and more consistent. Potential risks are minimal and relate to the small fluid boluses (temporary changes in blood pressure or heart rate); the test stops if the anesthesiologist has any safety concerns. There is no direct benefit to participants, but results may help guide fluid therapy for similar patients in the future. The study is being conducted at a single academic hospital in the Republic of Korea and plans to enroll about 300 adults.

Frequently Asked Questions

What is Paired Comparison of SVV and PVI Accuracy?

Paired Comparison of SVV and PVI Accuracy is a clinical trial registered under NCT07260890. Current status: COMPLETED.

What is the status of NCT07260890?

The current status of NCT07260890 (Paired Comparison of SVV and PVI Accuracy) is: COMPLETED.

When did Paired Comparison of SVV and PVI Accuracy start?

Paired Comparison of SVV and PVI Accuracy started on 2025-10-01.

Official Source

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Data sourced from ClinicalTrials.gov API. For the most current status, refer to the official record.