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Clinical Trial

Overnight TI in TLE

NCT: NCT07434986 · NOT_YET_RECRUITING

NCT IDNCT07434986
StatusNOT_YET_RECRUITING
Start Date2026-06-01
Completion2026-10-30

Brief Summary

The goal of this clinical trial is to gauge whether overnight, non-invasive temporal interference (TI) stimulation aimed at the hippocampus can reduce abnormal brain activity linked to seizures and improve sleep in adults with drug-resistant temporal lobe epilepsy. The main questions are: Does overnight TI stimulation lower seizure-related EEG activity during sleep? Does overnight TI stimulation improve sleep quality and sleep patterns measured overnight in the lab? Researchers will compare each participant's nights without stimulation to nights with active stimulation, and will also look at a night after stimulation ends to see whether any changes last. Participants will: Stay in-lab for six days for overnight sleep and EEG monitoring Have one night of monitoring without stimulation Receive TI stimulation during sleep for several nights Have another night of monitoring without stimulation after the stimulation nights Complete brief questionnaires and thinking/memory tasks before and after the stimulation nights Be checked for side effects and comfort during the study and at follow-up

Frequently Asked Questions

What is Overnight TI in TLE?

Overnight TI in TLE is a clinical trial registered under NCT07434986. Current status: NOT_YET_RECRUITING.

What is the status of NCT07434986?

The current status of NCT07434986 (Overnight TI in TLE) is: NOT_YET_RECRUITING.

When did Overnight TI in TLE start?

Overnight TI in TLE started on 2026-06-01.

Official Source

View on ClinicalTrials.gov →

Data sourced from ClinicalTrials.gov API. For the most current status, refer to the official record.