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Clinical Trial

Effectiveness of tTIs for Improving Consciousness in Patients With DoC

NCT: NCT07539740 · RECRUITING

NCT IDNCT07539740
StatusRECRUITING
Start Date2026-03-08
Completion2028-05-31

Brief Summary

The goal of this clinical trial is to learn if a new type of brain stimulation called theta-burst patterned temporal interference stimulation (tTIs) works to improve awareness in people with disorders of consciousness (DoC). The main questions it aims to answer are: 1. Does tTIs help people with disorders of consciousness show more signs of awareness? 2. Does tTIs improve the brain's ability to process information and connect different brain areas? Is tTIs safe and easy for people with disorders of consciousness to tolerate? Researchers will compare a group receiving active tTIs to a group receiving a "sham" stimulation (a look-alike stimulation that delivers no real current) to see if the real stimulation works better. Participants will:Receive either active tTIs or sham stimulation twice a day for 5 consecutive days (total of 10 sessions). Undergo brain activity tests (EEG) and physical exams to check their level of awareness before and after the 5 days of treatment. Have their progress followed by researchers through phone calls at 1, 3, and 6 months after the treatment ends.

Frequently Asked Questions

What is Effectiveness of tTIs for Improving Consciousness in Patients With DoC?

Effectiveness of tTIs for Improving Consciousness in Patients With DoC is a clinical trial registered under NCT07539740. Current status: RECRUITING.

What is the status of NCT07539740?

The current status of NCT07539740 (Effectiveness of tTIs for Improving Consciousness in Patients With DoC) is: RECRUITING.

When did Effectiveness of tTIs for Improving Consciousness in Patients With DoC start?

Effectiveness of tTIs for Improving Consciousness in Patients With DoC started on 2026-03-08.

Official Source

View on ClinicalTrials.gov →

Data sourced from ClinicalTrials.gov API. For the most current status, refer to the official record.