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Clinical Trial

Comparison of Rate of Tooth Movement Between MOPs vs MOPs & LLLT Combined

NCT: NCT07626580 · NOT_YET_RECRUITING

NCT IDNCT07626580
StatusNOT_YET_RECRUITING
Start Date2026-06
Completion2026-12
SponsorRiphah International University (OTHER)
First posted
Last updated

Brief Summary

Orthodontic treatment is often prolonged, requiring years to achieve desirable outcomes. The prolonged duration of treatment increases the risk of complications such as root resorption, periodontal damage, and patient non-compliance. To address these concerns, various methods have been explored to accelerate orthodontic tooth movement, including pharmacological agents, mechanical vibration, corticotomies, and minimally invasive techniques like Micro-Osteoperforations (MOPs) and Low-Level Laser Therapy (LLLT). Micro-Osteoperforations (MOPs) have gained popularity as a minimally invasive technique that enhances bone remodeling by inducing a localized inflammatory response, thereby accelerating tooth movement. Studies have shown that MOPs can effectively stimulate the expression of cytokines, increasing osteoclastic activity and facilitating rapid orthodontic tooth movement. However, the extent of its effectiveness varies among individuals, necessitating additional interventions to maximize efficiency. Low-Level Laser Therapy (LLLT), also known as photobiomodulation, is another promising adjunct in orthodontics. LLLT has been reported to enhance cellular activity, promote osteoblastic and osteoclastic function, and improve tissue healing, leading to accelerated tooth movement. Several studies suggest that LLLT alone can expedite orthodontic treatment, but its combination with MOPs has not been extensively explored. This study aims to compare the rate of orthodontic tooth movement between MOPs alone and MOPs combined with LLLT. By evaluating these two techniques, this research seeks to determine whether LLLT enhances the effectiveness of MOPs in accelerating tooth movement. The findings of this study could provide valuable insights into optimizing orthodontic treatment duration while minimizing potential risks and discomfort for patients.

Frequently Asked Questions

What is Comparison of Rate of Tooth Movement Between MOPs vs MOPs & LLLT Combined?

Comparison of Rate of Tooth Movement Between MOPs vs MOPs & LLLT Combined is a clinical trial registered under NCT07626580. Current status: NOT_YET_RECRUITING.

What is the status of NCT07626580?

The current status of NCT07626580 (Comparison of Rate of Tooth Movement Between MOPs vs MOPs & LLLT Combined) is: NOT_YET_RECRUITING.

When did Comparison of Rate of Tooth Movement Between MOPs vs MOPs & LLLT Combined start?

Comparison of Rate of Tooth Movement Between MOPs vs MOPs & LLLT Combined started on 2026-06.

Official Source

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