PACE Cognition Proof-of-Concept Study
NCT: NCT07769424 · NOT_YET_RECRUITING
Brief Summary
This proof-of-concept study will evaluate whether physiologic pacemaker programming improves cognitive function and health status in patients with symptomatic bradycardia who require permanent pacemaker implantation. Participants will be randomized to either standard pacemaker programming at 60 beats per minute or individualized physiologic rate pacing between 60 and 90 beats per minute using the myPACE algorithm. Cognitive function and health status will be assessed before pacemaker implantation and again at the routine 3-month pacemaker clinic visit. The primary outcome is change in Montreal Cognitive Assessment total score. The secondary outcome is change in SF-36 mental component summary score.
Frequently Asked Questions
What is PACE Cognition Proof-of-Concept Study?
PACE Cognition Proof-of-Concept Study is a clinical trial registered under NCT07769424. Current status: NOT_YET_RECRUITING.
What is the status of NCT07769424?
The current status of NCT07769424 (PACE Cognition Proof-of-Concept Study) is: NOT_YET_RECRUITING.
When did PACE Cognition Proof-of-Concept Study start?
PACE Cognition Proof-of-Concept Study started on 2026-10-01.
Official Source
View on ClinicalTrials.gov →Data sourced from ClinicalTrials.gov API. For the most current status, refer to the official record.