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Clinical Trial

NRP + ex Situ HMPO2 vs NRP Alone in DCD Kidney Transplantation

NCT: NCT07779187 · NOT_YET_RECRUITING

NCT IDNCT07779187
StatusNOT_YET_RECRUITING
Start Date2027-01-01
Completion2030-12-31
SponsorKarolinska University Hospital (OTHER)
First posted
Last updated

Brief Summary

The goal of this clinical trial is to learn if the combination of Normothermic Regional Perfusion (NRP) at the time of organ procurement with ex situ Hypothermic Oxygenated Perfusion (HMPO2) of kidneys recovered from donors after circulatory death (DCD) is superior to NRP alone. The researchers will learn if the combined use of these technologies provides a benefit in terms of kidney transplant outcomes. The researchers will also learn about the patient quality of life after these transplants and if the use of these technologies is cost efficient. The main questions it aims to answer are: * Does NRP +HMPO2 provides a better DCD kidney function at 1 year post-transplant compared to NRP alone. * Are the postoperative complications and outcomes different between the two groups? * Is the quality of life of recipients different between the two groups? * Is the use of NRP +HMPO2 a cost effective strategy? Researchers will compare NRP and HMPO2 with NRP alone to see if the combined use of the technologies provides better transplant outcomes. Participants will: * Receive a kidney treated with one of the two strategies. * Visit the clinic as per usual clinical practice for checkups and tests * Report on their quality of life pre and post transplant * Undergo a kidney biopsy at one year to forecast long term transplant function

Frequently Asked Questions

What is NRP + ex Situ HMPO2 vs NRP Alone in DCD Kidney Transplantation?

NRP + ex Situ HMPO2 vs NRP Alone in DCD Kidney Transplantation is a clinical trial registered under NCT07779187. Current status: NOT_YET_RECRUITING.

What is the status of NCT07779187?

The current status of NCT07779187 (NRP + ex Situ HMPO2 vs NRP Alone in DCD Kidney Transplantation) is: NOT_YET_RECRUITING.

When did NRP + ex Situ HMPO2 vs NRP Alone in DCD Kidney Transplantation start?

NRP + ex Situ HMPO2 vs NRP Alone in DCD Kidney Transplantation started on 2027-01-01.

Official Source

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Data sourced from ClinicalTrials.gov API. For the most current status, refer to the official record.