Synthetic Mesh for Prevention of HernIa After opEn Abdomen cLosure stuDy
NCT: NCT07835334 · NOT_YET_RECRUITING
Brief Summary
The aim of this clinical trial is to evaluate whether placement of a synthetic prophylactic onlay mesh during definitive fascial closure can reduce the incidence of incisional hernia in adult patients managed with an open abdomen approach following emergency surgery. The main questions it aims to answer are: * Does prophylactic mesh placement reduce the incidence of incisional hernia compared with fascial closure without mesh? * Does prophylactic mesh placement influence the occurrence of postoperative complications such as evisceration or surgical site infection? Researchers will compare patients undergoing definitive fascial closure with prophylactic mesh placement to those undergoing fascial closure without mesh in order to determine whether the mesh decreases the incidence of incisional hernia and associated complications. Participants will: * Undergo standard open abdomen management followed by definitive fascial closure. * Be randomly assigned to one of the two study groups: * Definitive fascial closure without prophylactic mesh. * Definitive fascial closure with placement of a synthetic prophylactic onlay mesh. * Attend clinical follow-up visits in the general surgery outpatient clinic. * Undergo clinical evaluations at 1, 6, and 12 months after surgery, including physical examination and, if necessary, imaging studies to detect incisional hernia or postoperative complications.
Frequently Asked Questions
What is Synthetic Mesh for Prevention of HernIa After opEn Abdomen cLosure stuDy?
Synthetic Mesh for Prevention of HernIa After opEn Abdomen cLosure stuDy is a clinical trial registered under NCT07835334. Current status: NOT_YET_RECRUITING.
What is the status of NCT07835334?
The current status of NCT07835334 (Synthetic Mesh for Prevention of HernIa After opEn Abdomen cLosure stuDy) is: NOT_YET_RECRUITING.
When did Synthetic Mesh for Prevention of HernIa After opEn Abdomen cLosure stuDy start?
Synthetic Mesh for Prevention of HernIa After opEn Abdomen cLosure stuDy started on 2026-09-01.
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Official Source
View on ClinicalTrials.gov →Data sourced from ClinicalTrials.gov API. For the most current status, refer to the official record.