临床试验

Pharmaco-Neuroimaging Studies of Approach/Avoidance Behaviors and Post-Mortem Studies: Pharmacological Manipulation

NCT：NCT05232032 · RECRUITING

NCT编号NCT05232032

状态RECRUITING

开始日期2025-02-01

完成时间2027-03-31

SponsorMclean Hospital (OTHER)

First posted2022-02-09

Last updated2026-05-18

简要摘要

The study will investigate whether a nociceptin receptor antagonist will normalize neural and behavioral processes of approach/avoidance decision-making in unmedicated individuals with major depressive disorder (MDD) and anxiety disorders. More specifically, the study aims to investigate dysregulation within (1) corticostriatal-midbrain circuitry and (2) nociceptin/orphanin FQ peptide and the nociceptin receptor (NOPR).

官方来源

在 ClinicalTrials.gov 上查看 →

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