临床试验

Transcutaneous Auricular Vagus Nerve Stimulation as a Treatment for Neuropathic Pain Following Spinal Cord Injury

NCT：NCT07588711 · NOT_YET_RECRUITING

NCT编号NCT07588711

状态NOT_YET_RECRUITING

开始日期2026-10-01

完成时间2028-08-30

SponsorLondon Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's (OTHER)

First posted2026-05-15

Last updated2026-05-15

简要摘要

This pilot randomized, double-blind, sham-controlled clinical investigation will evaluate the feasibility and safety of a 30-day home-based transcutaneous auricular vagus nerve stimulation (taVNS) intervention in adults with spinal cord injury (SCI) and neuropathic pain. Participants will be randomized to receive either active taVNS targeting the auricular branch of the vagus nerve or sham taVNS delivered to the earlobe. Primary outcomes include feasibility, safety, adherence, acceptability, and blinding success. Exploratory outcomes include changes in neuropathic pain, systemic inflammatory biomarkers, vagal tone assessed via heart rate variability, and quality of life.

官方来源

在 ClinicalTrials.gov 上查看 →

数据来自 ClinicalTrials.gov API。有关最新状态，请参阅官方记录。