臨床試驗

Transcutaneous Auricular Vagus Nerve Stimulation as a Treatment for Neuropathic Pain Following Spinal Cord Injury

NCT：NCT07588711 · NOT_YET_RECRUITING

NCT IDNCT07588711

狀態NOT_YET_RECRUITING

開始日期2026-10-01

完成時間2028-08-30

SponsorLondon Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's (OTHER)

First posted2026-05-15

Last updated2026-05-15

簡要摘要

This pilot randomized, double-blind, sham-controlled clinical investigation will evaluate the feasibility and safety of a 30-day home-based transcutaneous auricular vagus nerve stimulation (taVNS) intervention in adults with spinal cord injury (SCI) and neuropathic pain. Participants will be randomized to receive either active taVNS targeting the auricular branch of the vagus nerve or sham taVNS delivered to the earlobe. Primary outcomes include feasibility, safety, adherence, acceptability, and blinding success. Exploratory outcomes include changes in neuropathic pain, systemic inflammatory biomarkers, vagal tone assessed via heart rate variability, and quality of life.

官方來源

在 ClinicalTrials.gov 上查看 →

資料來自 ClinicalTrials.gov API。最新狀態請參閱官方紀錄。