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Essai clinique

Transcutaneous Auricular Vagus Nerve Stimulation as a Treatment for Neuropathic Pain Following Spinal Cord Injury

NCT : NCT07588711 · NOT_YET_RECRUITING

ID NCTNCT07588711
StatutNOT_YET_RECRUITING
Date de début2026-10-01
Achèvement2028-08-30
SponsorLondon Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's (OTHER)
First posted
Last updated

Résumé succinct

This pilot randomized, double-blind, sham-controlled clinical investigation will evaluate the feasibility and safety of a 30-day home-based transcutaneous auricular vagus nerve stimulation (taVNS) intervention in adults with spinal cord injury (SCI) and neuropathic pain. Participants will be randomized to receive either active taVNS targeting the auricular branch of the vagus nerve or sham taVNS delivered to the earlobe. Primary outcomes include feasibility, safety, adherence, acceptability, and blinding success. Exploratory outcomes include changes in neuropathic pain, systemic inflammatory biomarkers, vagal tone assessed via heart rate variability, and quality of life.

Source officielle

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