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Clinical Trial

Comparison of Pre- vs Post-dilution Haemodiafiltration in Children

NCT: NCT04210154 · COMPLETED

NCT IDNCT04210154
StatusCOMPLETED
Start Date2021-02-01
Completion2022-11-30
SponsorGreat Ormond Street Hospital for Children NHS Foundation Trust (OTHER)
First posted
Last updated

Brief Summary

Cardiovascular morbidity and mortality are increased in children on conventional haemodialysis. Haemodiafiltration (HDF) is a newer type of dialysis which has two main types (post-dilution and predilution HDF). Post-dilution HDF is associated with better vascular health, blood pressure and growth in children. Furthermore, pre-dilution HDF is shown to remove a wider spectrum of uremic toxin compared to post-dilution HDF in adults. The investigators need more data to define the optimum dialysis modality for children.

Official Source

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Data sourced from ClinicalTrials.gov API. For the most current status, refer to the official record.

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